WebJan 8, 2024 · Even though 80% of patients with High-Grade Serous Ovarian Cancer respond to standard first-line chemotherapy, a majority of them could relapse in the following five years due to a resistance to platinum. Human Epididymis protein 4 (HE4) is one of the most promising markers in predicting platinum therapy response. This pilot study aims to … WebMay 29, 2013 · A retrospective review was conducted of patients from three centers in Melbourne, Australia who had received oral cyclophosphamide treatment for recurrent ovarian cancer. The primary end-point was response rate to oral cyclophosphamide (150 mg p.o. day 1–14) based on Gynecologic Cancer InterGroup (GCIG) CA125 and/or …
Oral metronomic cyclophosphamide in advanced ovarian cancer…
WebCyclophosphamide (Cytoxan) is a drug prescribed for the treatment of certain cancers including breast cancer, leukemia, and ovarian cancer. Side effects, drug interactions, patient safety information, and pregnancy and breastfeeding information should be reviewed prior to taking any medication. WebMar 18, 2024 · Emese Zsiros, MD, PhD. Women with recurrent ovarian cancer treated with the combination of pembrolizumab (Keytruda), bevacizumab (Avastin), and metronomic cyclophosphamide had a 95% disease control rate and a 40% overall response rate, according to findings from an open-label phase II study presented during the 2024 SGO … mucus plug in early pregnancy
Paraplatin®/Cytoxan® a Possible Alternative for Ovarian Cancer
WebOral metronomic cyclophosphamide has gained increasing interest in recent years in the treatment of patients with recurrent ovarian cancer. We report the case of a 87-year-old and -frailty woman with advanced ovarian cancer, not eligible for surgery or standard first-line intravenous chemotherapy. The patient has received oral metronomic ... WebNov 19, 2024 · In a new article in JAMA Oncology, the researchers report that one-quarter of patients who received the combination of pembrolizumab (brand name Keytruda), … WebUses. Cyclophosphamide is used to treat various types of cancer. It is a chemotherapy drug that works by slowing or stopping cell growth.Cyclophosphamide also works by … mucus plug or bloody show